Mechanisms of microRNA?142 in mitochondrial autophagy and hippocampal damage in a rat model of epilepsy

摘要

Researchers have confirmed the microRNA (miRNA/miR)?epilepsy association in rodent models of human epilepsy via a comprehensive database. However， the mechanisms of miR?142 in epilepsy have not been extensively studied. In the present study， a rat model of epilepsy was first established by an injection of lithium chloride?pilocarpine and the successful establishment of the model was veri? fied via electroencephalogram monitoring.