Idiopathic full-thickness macular hole is a severe visual impairment disease. Pars plana vitrectomy remains the primary treatment option for idiopathic full-thickness macular holes, and over 90% idiopathic full-thickness macular holes are closed by vitrectomy surgery. However, the full-thickness macular hole may close spontaneously, with a good visual acuity progress. Since recent studies are small-sample studies and case reports, the characteristics for spontaneous closure of idiopathic full-thickness macular holes are not fully understood. Here, we review the articles in PubMed database from 1999 to 2018 and discuss the characteristic and the risk factors, especially OCT structure features, for spontaneous closure of idiopathic full-thickness macular holes.
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机译：特发性全厚的黄斑孔是一种严重的视觉损伤疾病。 Pars Plana Vitecomy仍然是特发性全厚的黄斑孔的主要治疗选择，并且通过玻璃体切除手术关闭超过90％的特发性全厚的黄斑孔。然而，全厚的黄斑孔可以自发地关闭，视力良好的进展。由于最近的研究是小型样本研究和病例报告，但没有完全理解发作性全厚黄斑孔的自发闭合特性。在这里，我们从1999年到2018年审查了PubMed数据库的文章，并讨论了特征和风险因素，特别是OCT结构特征，用于发作性全厚的黄斑孔的自发闭合。
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