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Transanal total mesorectal excision for rectal cancer: Surgical outcomes and short-term oncological outcomes in a single-institution consecutive series

机译:直肠癌的正常介性切除:手术结果和单机连续系列中的短期肿瘤结果

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Introduction: Rectal cancer surgery is continuously evolving. Transanal total mesorectal excision (TaTME) is a relatively new surgical approach with possible advantages in comparison to current standard surgical techniques. Several studies in recent years have validated this approach regarding safety and effectiveness. We describe our initial experience with TaTME evaluating surgical parameters, post-operative outcomes and short-term oncological outcomes. Methods: This is a retrospective study reviewing all patients who underwent TaTME in a single institution from May 2015 to April 2018. Results: The cohort included 25 patients with an average age of 60.4 (range: 40–86), of which 13 (52%) patients were male. The average body mass index was 26.1. The overall 30-day morbidity rate was 40%, with 20% (five cases) being severe complications, defined by Clavien–Dindo Grade of 3b or above. There were three major interoperative complications. Four cases (16%) required reoperation during the first 30 post-operative days. The median length of stay was 8 days. The surgery duration was on average 296 min (range: 205–510). Negative resection margins were achieved in all patients. At a median follow-up period of 14 months, there were no local recurrences, and 4 cases (16%) had a distant recurrence. Conclusion: This study describes our initial experience with TaTME, which requires a substantial learning curve to minimise complications and morbidity. Oncological outcomes as expressed by the resection margins, number of lymph nodes harvested and local recurrence rates were all comparable to previously published data.
机译:简介:直肠癌手术不断发展。 TransAnal总介性切除(TATME)是一种相对较新的手术方法,与当前标准手术技术相比可能的优点。近年来的几项研究已经验证了关于安全性和有效性的这种方法。我们描述了我们对Tatme评估手术参数,术后结果和短期肿瘤结果的初步体验。方法:这是一项回顾性研究,审查了从2015年5月至2018年5月在单一机构中接受了TATME的所有患者。结果:队列包括25名平均年龄为60.4(范围:40-86)的患者,其中13(52) %)患者是男性。平均体重指数为26.1。整体30天的发病率为40%,20%(五种情况)是严重的并发症,由Clavien-Dindo等级为3B或以上定义。有三种主要的互操作并发症。在手术后的30次后30例期间,四种情况(16%)需要重新组合。中位数的逗留时间为8天。手术持续时间平均为296分钟(范围:205-510)。在所有患者中取得了负切除余量。在14个月的中位随访期间,没有局部复发,4例(16%)有遥远的复发。结论:本研究描述了我们对Tatme的初步体验,需要大量的学习曲线来最大限度地减少并发症和发病率。由切除边缘表达的肿瘤学结果,收获的淋巴结数和局部复发率的数量都与先前公布的数据相当。

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