A new phenolic glycoside, 3, 5 - dihydroxy - 2- (hydroxyl methyl) - 6-(3,4,5-trimethoxy phenoxy)tetrahydro-2H-pyran-4-yl, 4-hydroxy-3-methoxy benzoate have been isolated from the dried bark ofSymplocos racemosa. The structure was identified by extensive spectral analysis, especially FT-IR, GC-MS,1H NMR and13C NMR techniques. The method of isolation was simple, cost effective and efficient. The preliminary bioactivity of the compound was also evaluated. The ethanolic extract ofSymplocos racemosa(EESR) was investigated for its anti-pyretic activity against brewer’s yeast induced pyrexia. The antipyretic effect of EESR (measured as % reduction in body temperature) was compared with paracetamol (100 mg/kg, orally). EESR in dose of 200 mg/kg caused significant decrease in body temperature of rats. This study has established the antipyretic activity ofSymplocos racemosaand thus, justifies the ethnic uses of the plant.
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