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Fact file of levofloxacin and risk factors of OH affiliated matrix impurity, disregards impurity and specified impurity associated undetectable impurity an extended study of second generation antibiotics

机译:左草氧化嘧啶的事实文件和OH相关基质杂质的危险因素,无视杂质和特定杂质相关的未定例杂质对第二代抗生素的延长研究

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To highlight this important part of the research process, we asked research scientists to speak about their own experiences with failure. Research scientist explains why considers non-significant and negative studies to be important parts of publication history. Licensed data by USFDA Levofloxacin, but pregnancy category risk not ruled out. Levofloxacin identified by IUPAC (3S)-9-Fluor-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]chinolin-6-carbonsure, by the end of 6- carboxylic acid group. Legal status is general prescription only. Levofloxacin was approved for medical use in the United States in 1996. It is on the world health organization's list of essential medicines, the most effective and safe medicines needed in a health system. It is available as a generic medication. The wholesale cost in the developing world is about 0.44 to 0.95 USD per week of treatment. For patients with these conditions, OH should be inherent impurity seen in levofloxacin. Levofloxacin, sold under the trade names Levaquin among others, is an antibiotic. It is used to treat a number of bacterial infection including acute bacterial, sinusitis, Pneumonia and urinary infection, chronic prostatitis.
机译:为了强调这一重要部分的研究过程,我们要求研究科学家谈论自己的失败经验。研究科学家解释了为什么认为非重大和消极研究是出版历史的重要部分。 USFDA左氧氟沙星的许可数据,但怀孕类风险未排除在外。由Iupac(3S)-9-氟-3-甲基-10-(4-甲基-1-哌嗪基)-7-氧代-2,3-二氢-7H-[1,4]恶化氨基鉴定左氧氟沙星[2,3 ,4-IJ] Chinolin-6-碳结构,在6-羧酸基团的末端。法律地位只是一般处方。左氟醚于1996年批准在美国批准医疗用途。它是世界卫生组织的基本药物清单,卫生系统所需的最有效和安全的药品。它可作为通用药物提供。发展中国家的批发成本每周约为0.44至0.95美元。对于这些条件的患者,oh应该是在左氧氟沙星中看到的固有杂质。在商品名列莱西洛昔林莱伐香阁等左旋氧化嘧啶是一种抗生素。它用于治疗许多细菌感染,包括急性细菌,鼻窦炎,肺炎和泌尿感染,慢性前列腺炎。

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