Efficacy of rapid bowel preparation with new 1 L polyethylene glycol ascorbate solution in severe acute lower GI bleeding

摘要

According to American guidelines, 4 to 6 liters of poly- ethylene glycol (PEG)-based iso-osmolar solution should be rapidly administered over 3 to 4 hours until rectal effluent is clear; also, a nasogastric tube is used to facilitate the instillation in high-risk patients.' However, the high volume delays the procedure, and it is poorly acceptable to patients. Recently, a very-low-volume hyperosmolar bowel preparation, based on a combination of ascorbate with 1 L PEG (PEG-Asc), has been validated in randomized trials, showing superiority compared with 2 L PEG-Asc, tri- sulfate, and sodium picosulfate with magnesium citrate.