Mechanism of Action of a Peroxisome Proliferator-Activated Receptor (PPAR)-δ Agonist on Lipoprotein Metabolism in Dyslipidemic Subjects with Central Obesity

Esther M. M. Ooi; Gerald F. Watts; Dennis L. Sprecher; Dick C. Chan; P. Hugh R. Barrett

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Mechanism of Action of a Peroxisome Proliferator-Activated Receptor (PPAR)-δ Agonist on Lipoprotein Metabolism in Dyslipidemic Subjects with Central Obesity

机译：过氧化物体增殖物激活受体（PPAR）-δ激动剂对中央肥胖症血脂血糖受试者脂蛋白代谢的作用机制

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Context:Dyslipidemia increases the risk of cardiovascular disease in obesity. Peroxisome proliferator-activated receptor (PPAR)-δ agonists decrease plasma triglycerides and increase high-density lipoprotein (HDL)-cholesterol in humans.

机译：背景：血脂过度血症增加肥胖症中心血管疾病的风险。过氧化物体增殖物激活受体（PPAR）-δ激动剂可降低血浆甘油三酯并增加人类中的高密度脂蛋白（HDL）硫醇。

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《The journal of clinical endocrinology and metabolism》 |2011年第10期|共9页
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Esther M. M. Ooi; Gerald F. Watts; Dennis L. Sprecher; Dick C. Chan; P. Hugh R. Barrett;
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1. Effects of peroxisome proliferator-activated receptor (PPAR)-α and PPAR-γ agonists on glucose and lipid metabolism in patients with type 2 diabetes mellitus [J] . M. Bajaj, S. Suraamornkul, L. J. Hardies, Diabetologia . 2007,第8期

机译：过氧化物酶体增殖物激活受体（PPAR）-α和PPAR-γ激动剂对2型糖尿病患者糖脂代谢的影响
2. The dual peroxisome proliferator-activated receptor alpha/gamma agonist tesaglitazar further improves the lipid profile in dyslipidemic subjects treated with atorvastatin. [J] . Tonstad S, Retterstol K, Ose L, Metabolism: Clinical and Experimental . 2007,第9期

机译：双过氧化物酶体增殖物激活受体α/γ激动剂替沙格列扎可进一步改善用阿托伐他汀治疗的血脂异常受试者的脂质分布。
3. Peroxisome proliferator-activated receptorα (PPARα) agonists down-regulate α2-macroglobulin expression by a PPARα-dependent mechanism [J] . Maria del Carmen Gonzalez, J. Christopher Cotton, Russell C. Cattley, Biochimie . 2009,第8期

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4. Molecular Docking Studies of Flavonoids of Noni Fruit (Morinda citrifolia L.) to Peroxisome Proliferator-Activated Receptor-Gamma (PPAR_γ) [C] . Fikry Awaluddin, Andrianopsyah Mas Jaya Putra, Supandi International Conference on Computation for Science and Technology . 2015

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5. Peroxisome Proliferator-activated Receptor-γ (PPARγ) Agonists: Potential Novel Treatment for HIV-1 Associated Brain Inflammation [D] . Omeragic, Amila . 2020

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7. Mechanism of Action of a Peroxisome Proliferator-Activated Receptor (PPAR)-δ Agonist on Lipoprotein Metabolism in Dyslipidemic Subjects with Central Obesity [O] . Esther M. M. Ooi, Gerald F. Watts, Dennis L. Sprecher, 2011

机译：过氧化物体增殖物激活受体（PPAR）-δ激动剂对中央肥胖症血脂血糖受试者脂蛋白代谢的作用机制

Mechanism of Action of a Peroxisome Proliferator-Activated Receptor (PPAR)-δ Agonist on Lipoprotein Metabolism in Dyslipidemic Subjects with Central Obesity

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