Digital pacinian neuroma in a patient with myeloma

摘要

We present a case of Pacinian Neuroma (PN) associated with multiple myeloma (MM) in a 57-year-old man witha 6-month history of painful swelling of his fingers. Physical examination revealed definite palpable nodules andmoderate swelling over the first phalanx of all his fingers. A biopsy confirmed the diagnosis of PN. The patient reportedchronic back pain. Radiologically, a severe demineralization was found. MM was suspected. The results of completeblood count and biochemistry panels were within normal limits. Otherwise, immunoelectrophoresis demonstratedmonoclonal light chains in blood and urine. Bone marrow biopsy was consistent with MM. The patient successfullyunderwent an autologous stem cell transplant with good response. A slight decrease in the size in PN was noted. Tothe best of our knowledge, no case of PN associated with MM had been reported. This occurrence may be accidental.However, further studies are required in order to explain this association.