Evaluation of D-Dimer Level in Sudanese Patients with Chronic Liver Disease in IbnSina Hospital

摘要

Background: Chronic liver disease is a disease process of the liver that involves a process of progressive destruction and regeneration of the liver parenchyma leading to fibrosis and cirrhosis chronic liver disease refers to disease of the liver which had lasted over a period of 6 months. This study was conducted to evaluate the D-dimer levels among Sudanese patients with Chronic Liver Diseases. Materials and Method: In IbnSina hospital, Khartoum state, Sudan, a case control study was conducted. For this study, 100 participants were selected, 70 of them were patients known diagnosed by chronic liver diseases as a test group. Other 30 participants were normal healthy individual as control group. The plasma D-dimer level was measured by using MINDRAY auto analyzer BS 380). Results: In this study, the plasma D-dimer level has statistically significantly higher in chronic liver diseases patients (mean ± SD 0.634 ± 0.215 ug/l) compared to normal healthy control group (mean ± SD 0.223 ± 0.077 ug/l) with P value 0.000. Conclusion: The present study revealed that the D-dimer levels were statistically significant higher in chronic liver diseases patients.