Reproducibility, reliability and variability of FA and MD in the older healthy population: A test-retest multiparametric analysis

摘要

Highlights?In older healthy subjects, FA and MD show overall good test-retest reliability & reproducibility.?MD is sistematically more reproducible than FA across the entire brain anatomy.?FA is more reliable than MD in subcortical white matter regions.?In high reliability & low reproducibility regions, variability between subjects is high and statistical power is low.?In low reliability & high reproducibility regions, variability between subjects is low and statistical power is high.