Studies on the Deoxyribonucleic Acid of Serratia marcescens

摘要

SUMMARY A method for the quantitative isolation of pure highly polymerized DNA from Serratia marcescens, based on Kirby's phenol extraction procedure (Kirby, 1956, 1957), has been developed. No statistically significant differences were detected in the base composition or sequence between the DNA of a wild and a mutant strain of the organism. 6-Methyl-aminopurine was found in the DNA of Serratia marcescens. The properties of this base and its N-nitroso derivative were compared with those of a synthetic sample.