A case of mammary analogue secretory carcinoma of the parotid gland: A case report

摘要

Rationale: Mammary analogue secretory carcinoma is a low grade salivary gland malignancy, first described by Skalova et al in 2010. The histological, immunohistochemical, and molecular characteristics of this tumor resemble those of secretory carcinoma of the breast. Patient concerns: A 40-year-old male patient without any specific past history came with complaints of 4 cm-sized hard, fixed, right infra-auricular mass without tenderness. There was no enlarged or enhancing lymph node in both neck. Diagnoses: Fine needle aspiration biopsy was done for right parotid mass and pathologic report was ”lymphocytes only” that suggested benign or low-grade malignant parotid tumor. Interventions: Partial parotidectomy including mass excision was performed. Operative finding showed hard bluish mass located in deep lobe of right parotid gland . Outcomes: Final pathologic report revealed secretory carcinoma of parotid gland . Homogenous eosinophilic secretions were identified inside microcystic structure. The immunophenotype was positive for epithelial membrane antigen, vimentin, S-100 protein. After 15 months of the surgery, the patient showed negative evidence of disease state. Lessons: We present here a case of mammary analogue secretory carcinoma of the parotid gland to help further characterize this rare tumor.