Diethyl 4-(1H-indol-3-yl)-2,6-dimethyl-1,4-di-hydro-pyridine-3,5-di-carboxyl-ate

摘要

In the title compound, C 21 H 24 N 2 O 4 , the 1,4-di-hydro-pyridine ring adopts a very flattened boat conformation, with the 3-pyridine substituent in an axial orientation. The pyridine ring is almost orthogonally twisted relative to the 1,4-di-hydro-pyridine skeleton by 85.97?(2)°. In the crystal, pairs of N—H?O hydrogen bonds form inversion dimers enclosing R 2 2 (16) rings. Pairs of inter-molecular N—H?O hydrogen bonds link the dimers into chains along [100].