Possibilities of Menopausal Hormone Therapy in the Correction of Menopausal Disorders in Women with Thyroid Diseases in Postmenopause

摘要

Thyroid diseases are the most common diseases of the endocrine system, especially in women older than 45 years. However, often their manifestation falls on the perimenopausal period. When examining women who complained of symptoms characteristic of menopause, thyroid diseases were detected in 28% of all women examined. Diseases of the thyroid gland mainly affect women; their frequency in the female population is 5-20 times higher than in men. In addition, the prevalence of most thyroid diseases increases with age. In the Republic of Uzbekistan, the situation does not differ from global trends. In women with of hypothyroidism and AIT, manifestations of pathological climacteria were observed, mainly of moderate and mild severity. The treatment of hypothyroidism in postmenopausal women depends on several conditions: the presence of symptoms, the severity of hypothyroidism, the coexisting risk of cardiovascular disease, and the patient's age. All women showed significant positive changes in menopausal disorders after MHT treatment. Our study shows the safety of menopausal hormone therapy in women with thyroid diseases.