Prognostic Criteria of Severity of Systemic Inflammatory Response Syndrome in Newborns

摘要

The authors conducted a study on the cytokine status of newborns with perinatal infections in the neonatal period of adaptation. IL-8 acts as one of the criteria for the severity of systemic inflammatory response in newborns. The authors argue that the level of IL-8 in urine can predict the outcome of both early and late neonatal period in newborns with infections. The criterion of severity of both early and late neonatal period in newborns with infections is the concentration of IL-8 in the urine. Prognostic criteria for the severity of CIRS in newborns with non-communicable diseases are: In the early neonatal period: - TNF-α > 20.3 PG / ml in urine; - INF-γ > 9.2 PG / ml in urine; In the late neonatal period: - IL-6 > 56.9 PG / ml in blood; - TNF-α >39.0 PG/ml in blood; - IL-8 >1.1 PG / ml in urine.