Effect of Hydroxychloroquine in Diabetes Mellitus: A Review on Preclinical and Clinical Trial Studies

摘要

Hydroxy chloroquine is a commonly used drug for its anti-malarial and anti-rheumatic effects. It is shown to have hypoglycemic effects and is proven to reduce the risk of Diabetes mellitus. Diabetes is seen in majority of population all over the world. Often efforts for diabetes prevention are limited by long term use of costly medicines and their potential side effects and poor adherence to lifestyle modifications. Hydroxy chloroquine is a generic and low cost medicine which can help treat diabetes patients effectively and also prevent progression in risk patients from pre diabetes to diabetes. Here our objective is to provide the information from clinical and preclinical studies and case reports on this topic and discuss them under a single review article.