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Self-reported smoking among adolescents: How accurate is it with the urine cotinine strip test?

机译:青少年中自我报告的吸烟:用尿cotinine条带测试有多准确?

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Background & ObjectiveIn the local setting, the prevalence of smoking among adolescents varies, as it is based only on self-reporting without biomarker validation. The objective of the present study was to determine the accuracy of self-reported smoking among adolescents as compared to that of the urine cotinine strip test.MethodsWe performed a cross-sectional study of 314 adolescents aged 16 years from February 2015 to April 2015 in Putrajaya, Malaysia. The accuracy of self-reporting was assessed using a data collection sheet and was validated by the urine cotinine strip test. Three schools were chosen by the simple random method, where all Form 4 students constituted the sample unit. The kappa statistic was used for determining agreement between self-reporting and urine cotinine strip testing.ResultsThere was a substantial agreement between self-reporting and the urine cotinine strip test (kappa?=?0.757, 95% confidence interval [CI]: 0.63, 0.88); there was 95.86% overall agreement. The prevalence of self-reported smoking was 8% (95% CI: 7.47, 8.53) and that of urine cotinine strip testing was 10.8% (95% CI: 10.20, 11.41). There was a discrepancy with the results of the urine cotinine strip test in 8% of self-reported smokers and 3.8% of self-reported nonsmokers. Self-reporting had 67.6% sensitivity and 99.3% specificity as compared to those of urine cotinine strip testing and had 92% positive predictive value and 96.2% negative predictive value.ConclusionSelf-reporting can be used to assess smoking status but should be used with care among adolescents. Urine cotinine strip test validation of self-reporting enables the measurement of the true prevalence of smoking among adolescents.
机译:背景和OustomeIn本地环境,青少年吸烟的患病率不同,因为它只基于没有生物标记验证的自我报告。本研究的目的是确定与尿液中的尿素线条测试相比青少年自我报告的吸烟的准确性.Thodswe在2015年2月至2015年4月在普特拉贾纳进行了314岁的青少年的横截面研究马来西亚。使用数据收集表评估自我报告的准确性,并由尿cotinine条测试验证。通过简单的随机方法选择了三所学校,其中所有表格4学生构成了样本单元。 Kappa统计数据用于确定自我报告和尿液中的尿素内剥离测试之间的协议。自我报告和尿cotinine条纹测试之间是一项大幅项协议(kappa?= 0.757,95%置信区间[CI]:0.63, 0.88);总协议有95.86%。自我报告的吸烟的患病率为8%(95%CI:7.47,8.53),尿素素带测试的患病率为10.8%(95%CI:10.20,11.41)。尿液含有尿素线的结果存在于8%的自我报告的吸烟者和3.8%的自我报告的非报道中的结果存在差异。与尿喹啉条带测试相比,自我报告具有67.6%和99.3%的特异性,并且具有92%的阳性预测值和96.2%的阴性预测值。结论可用于评估吸烟状态,但应与护理使用在青少年中。自我报告的尿cotinine条带测试验证能够测量青少年吸烟的真正患病率。

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