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The clinical status and survival in elderly dialysis: example of the oldest region of France

机译:老年人透析的临床状态和生存:法国最古老的地区的典范

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Background The number of elderly (≥75?years) patients with end-stage renal disease (ESRD) has increased markedly, including in the Limousin region, which has the oldest population in France. We retrospectively compared outcomes in elderly and non-elderly ESRD patients who started dialysis during two time periods. Methods Baseline clinical characteristics, care, and survival rates were assessed in 557 ESRD patients aged ≥75 and Results Of the 557 patients, 343 and 214 were vs 69.5?years [IQR 57.4-77.4?years] p?=?0.001) and the proportion aged ≥75?years (44.7% vs 32.8%, p?=?0.004) were significantly higher in 2005–2007 than in 2002–2004. Improved initial status during 2005–2007 was observed only in patients ≥75?years, with a decrease in some co-morbidities, improved walking and better preparation for dialysis. Mortality rates were significantly lower in 2005–2007 than in 2002–2004 (hazard ratio 0.81, 95% confidence interval 0.69-0.95; p?=?0.008), with the difference due to factors associated with clinical status and care. Conclusions Improved initial clinical status and better preparation for dialysis, accompanied by increased survival, were observed for patients ≥75?years who started dialysis more recently, perhaps because of early referral to a nephrologist.
机译:背景技术患有末期肾病(ESRD)的老年人(≥75岁)(ESRD)的数量明显增加,包括在豪华轿宾地区,这是法国最古老的人口。我们回顾性地比较了在两次开始透析的老年人和非老年人ESRD患者的结果。方法在≥75岁≥75岁的557名ESRD患者中评估了基线临床特征,护理和存活率,557名患者的结果,343和214名为69.5岁?年[IQR 57.4-77.4吗?=?0.001)和比例≥75?年龄(44.7%vs 32.8%,P?= 0.004)在2005 - 2007年明显高于2002 - 2004年。仅在≥75岁时观察到2005 - 2007年期间的初始状态改善了≥75岁的患者,这是一些共同生命,改善的行走,更好地透析准备。 2005 - 2007年死亡率明显低于2002-2004(危险比0.81,95%置信区间0.69-0.95; p?= 0.008),由于与临床状态和护理相关的因素,差异。结论对于患者≥75岁的患者,伴随着生存增加的术语伴随的初期临床状况和更好的准备,伴随着增加的存活,≥75岁,患者最近开始透析,也许是因为早期转诊肾脏学家。

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