The delta neutrophil index predicts development of multiple organ dysfunction syndrome and 30-day mortality in trauma patients admitted to an intensive care unit: a retrospective analysis

摘要

No studies have examined the role of delta neutrophil index (DNI) reflecting on immature granulocytes in determining the severity of multiple organ dysfunction (MODS) and short-term mortality. This study investigated the utility of the automatically calculated DNI as a prognostic marker of severity in trauma patients who were admitted to an intensive care unit (ICU). We retrospectively analysed prospective data of eligible patients. We investigated 366 patients. On multivariable logistic regression analysis, higher DNI values at 12?h (odds ratio [OR], 1.079; 95% confidence interval [CI]: 1.037–1.123; p 3.25% at 12?h (OR, 12.7; 95% CI: 6.12–26.35; p 5.3% at 12?h was significantly associated with an increased risk of 30-day mortality (HR, 18.111; 95% CI, 6.988–46.935; p??0.001). The DNI is suitable for rapid and simple estimation of the severity of traumatic injury using an automated haematologic analyser without additional cost or time.