Determining Heterochromatic Flicker Photometry Frequency for Macular Pigment Optical Densitometry by Critical Flicker Fusion Frequency

摘要

Accurate clinical assessment of Macular Pigment Optical Density (MPOD) using Heterochromatic Flicker Photometry (HFP) requires the HFP stimulus be presented at or near a specific a??ideala?? frequency. If the frequency is too low, fusion never occurs and the task is difficult for naive patients. If the frequency is too high, fusion occurs in a wide range of values, and measurement error is high. Determining this frequency is time consuming and difficult to determine in a clinical setting. Critical Flicker Fusion (CFF) frequency is easy to assess using standard densitometry equipment in naive patients. By correlating CFF and the a??ideala?? frequency for HFP densitometry for a given densitometer, HFP frequency selection can be made quickly and accurately from the comparatively easier CFF assessment. A methodology for determining a??ideala?? HFP frequency was developed using a Macular Metrics II (tm) Macular Pigment Optical Densitometer. a??Ideala?? HFP frequencies show positive correlation to CFF frequency allowing a straightforward algorithm to be derived.