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Comparative Evaluation of Antibacterial Efficacy of Six Indian Plant Extracts against Streptococcus Mutans

机译:六种印度植物提取物对变形链球菌的抗菌效果比较评价

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Introduction: To assess the antimicrobial efficacy of six plant extracts of Indian origin often used as traditional medicine against standard strains of Streptococcus mutans. Materials and Methods: The antimicrobial activity of six plant extracts was determined by the agar well diffusion method. The minimum inhibitory concentration (MIC) for the crude (raw), Organic solvent based, aqueous extracts was determined by the agar well diffusion method. Results: Out of all the six extracts evaluated, organic solvent based and aqueous extracts of all the extracts were found to have variable antimicrobial activities against the oral pathogen. The crude extract of Garlic was the most effective against Streptococcus mutans with the highest zone of inhibition (24.62 mm) followed by the aqueous extract of Amla (19.47mm) and organic solvent based extract of Ginger (18.76 mm). Conclusion: Despite of the fact that the extracts were not pure compounds and antimicrobial results were obtained. This recommends the potency of these extracts. The figment of the derivation of antimicrobial compounds from plants seems lucrative as it will lead to the development of a phytomedicine to act against microbes.
机译:简介:为了评估六种常用作传统药物的印度植物提取物对变形链球菌标准菌株的抗菌效果。材料和方法:用琼脂井扩散法测定六种植物提取物的抗菌活性。通过琼脂井扩散法确定粗品(原料),有机溶剂基水性提取物的最低抑菌浓度(MIC)。结果:在所评估的所有六种提取物中,所有提取物的有机溶剂基提取物和水性提取物被发现对口腔病原体具有不同的抗菌活性。大蒜的粗提物对变形链球菌的抑制效果最高(24.62 mm),对变形链球菌的抑制效果最强,其次是Amla的水提物(19.47mm)和生姜的有机溶剂基提物(18.76 mm)。结论:尽管提取物不是纯化合物,但仍获得了抗菌效果。这建议这些提取物的效力。从植物中衍生出抗微生物化合物的方法似乎很有利可图,因为它将导致植物药的发展来对抗微生物。

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