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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Measles Outbreak in the Adolescent Population - Matter of Concern? LC20-LC23
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Measles Outbreak in the Adolescent Population - Matter of Concern? LC20-LC23

机译:青少年人口中的麻疹暴发-是否值得关注? LC20-LC23

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Introduction: Measles is a disease predominantly seen in young children and infants. It is an unusual occurrence of the disease in the adolescent population warranting an investigation. This would help understand the possible cause-effect relation, changing epidemiology of the disease and immunity gaps to initiate targeted interventional strategies. Aim: To determine the time, place and person distribution of an outbreak and calculate the attack rates and vaccine efficacy. Materials and Methods: Investigation of an outbreak was conducted by an emergency rapid response team following the report of a case of measles on 18th November 2013, in and around the campus of the study university in search of suspects and undetected cases. W.H.O developed standard outbreak investigation formats, were used for obtaining the data. The subjects were chosen by purposive sampling. All the contacts of the cases were approached along with a house to house survey in the surrounding residential area for active case finding. Measles was clinically diagnosed based on the standard case definition of measles as per the WHO guidelines and confirmed through measurement of measles specific IgM antibody levels in the serum of suspected/clinically confirmed cases. Results: The outbreak lasted for duration of six weeks during which a total of 20 laboratory confirmed cases were found. Most of the cases were in the age group of 21-25 years. The overall attack rate was 3.5% and vaccine efficacy was calculated to be 75%. Conclusion: There is an epidemiological shift in the age of occurrence of measles in the region among students coming from various regions of the country staying predominantly in hostels.
机译:简介:麻疹是一种主要在幼儿和婴儿中发现的疾病。这是该疾病在青少年人群中的不寻常发生,需要进行调查。这将有助于了解可能的因果关系,疾病流行病学的变化和免疫缺陷,从而启动有针对性的干预策略。目的:确定爆发的时间,地点和人的分布,并计算出发作率和疫苗效力。材料和方法:2013年11月18日,在研究大学校园内外附近,由紧急事件快速反应小组对麻疹病例进行了调查,以寻找可疑和未发现的病例。 W.H.O开发了标准的暴发调查格式,用于获取数据。通过有目的抽样选择受试者。与案件的所有联系人进行了联系,并在周围居民区进行了逐户调查,以积极寻找案件。根据WHO指南根据麻疹的标准病例定义对麻疹进行临床诊断,并通过测量可疑/临床确诊病例血清中的麻疹特异性IgM抗体水平进行确诊。结果:暴发持续了六个星期,在此期间共发现了20个实验室确诊病例。大多数病例在21-25岁年龄段。总体发作率为3.5%,疫苗效力经计算为75%。结论:该地区主要来自宿舍的学生来自该地区的麻疹发病年龄发生了流行病学变化。

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