Distinct genetic code expansion strategies for selenocysteine and pyrrolysine are reflected in different aminoacyl‐tRNA formation systems

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Distinct genetic code expansion strategies for selenocysteine and pyrrolysine are reflected in different aminoacyl‐tRNA formation systems

机译：硒代半胱氨酸和吡咯赖氨酸的不同遗传密码扩展策略反映在不同的氨酰基tRNA形成系统中

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Selenocysteineandpyrrolysine,knownasthe21stand22ndaminoacids,aredirectlyinsertedintogrowingpolypeptidesduringtranslation.SelenocysteineissynthesizedviaatRNA‐dependentpathwayanddecodesUGA(opal)codons.TheincorporationofselenocysteinerequirestheconcertedactionofspecificRNAandproteinelements.Incontrast,pyrrolysineisligateddirectlytotRNAPylandinsertedintoproteinsinresponsetoUAG(amber)codonswithouttheneedforcomplexre‐codingmachinery.HerewereviewthelatestupdatesonthestructureandmechanismsofmoleculesinvolvedinSec‐tRNASecandPyl‐tRNAPylformationaswellasthedistributionofthePyl‐decodingtrait...

机译：Selenocysteineandpyrrolysine，knownasthe21stand22ndaminoacids，aredirectlyinsertedintogrowingpolypeptidesduringtranslation.SelenocysteineissynthesizedviaatRNA-dependentpathwayanddecodesUGA（蛋白石）codons.TheincorporationofselenocysteinerequirestheconcertedactionofspecificRNAandproteinelements.Incontrast，pyrrolysineisligateddirectlytotRNAPylandinsertedintoproteinsinresponsetoUAG（琥珀色）codonswithouttheneedforcomplexre-codingmachinery.HerewereviewthelatestupdatesonthestructureandmechanismsofmoleculesinvolvedinSec-tRNASecandPyl-tRNAPylformationaswellasthedistributionofthePyl-decodingtrait ...

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《FEBS Letters》 |2010年第2期|共8页
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1. Distinct genetic code expansion strategies for selenocysteine and pyrrolysine are reflected in different aminoacyl-tRNA formation systems. [J] . Yuan J, ODonoghue P, Ambrogelly FEBS letters. . 2010,第2期

机译：硒代半胱氨酸和吡咯赖氨酸的不同遗传密码扩展策略反映在不同的氨酰基-tRNA形成系统中。
2. Erratum to: "Expanding Genetic Code: Aminoacids 21 and 22, Selenocysteine and Pyrrolysine" (Russ. J. Genet, (2011), 46, 8(899-916), 10.1134/S1022795411140018) [J] . Lukashenko N.P. Russian journal of genetics . 2011,第1期

机译：勘误至：“扩展的遗传密码：氨基酸21和22，硒代半胱氨酸和吡咯赖氨酸”（Russ。J. Genet，（2011），46，8（899-916），10.1134 / S1022795411140018）
3. Expanding Genetic Code: Amino Acids 21 and 22, Selenocysteine and Pyrrolysine [J] . Lukashenko N.P. Russian journal of genetics . 2010,第8期

机译：扩展的遗传密码：氨基酸21和22，硒代半胱氨酸和吡咯赖氨酸
4. Origin of most primitive mRNAs and genetic codes via interactions between primitive tRNA ribozymes. [C] . Ohnishi K, Hokari S, Shutou H, Workshop on Genome Informatics . 2002

机译：通过原始TrNA核酶之间的相互作用来起源于最原始MRNA和遗传码。
5. Forward genetic screening reveals that SB505124 blocks Toxoplasma gondii growth by simultaneously inhibiting distinct host- and parasite-encoded kinases. [D] . Brown, Kevin M. 2013

机译：正向遗传筛选显示，SB505124通过同时抑制不同的宿主和寄生虫编码激酶来阻断弓形虫的生长。
6. Distinct genetic code expansion strategies for selenocysteine and pyrrolysine are reflected in different aminoacyl-tRNA formation systems [O] . Jing Yuan, Patrick O’Donoghue, Alex Ambrogelly, -1

机译：为硒代半胱氨酸和吡咯不同遗传密码扩张战略反映在不同的氨酰-tRNa形成系统
7. Distinct genetic code expansion strategies for selenocysteine and pyrrolysine are reflected in different aminoacyl-tRNA formation systems [O] . Yuan Jing, O’Donoghue Patrick, Ambrogelly Alex, 2010

机译：硒代半胱氨酸和吡咯赖氨酸的不同遗传密码扩展策略反映在不同的氨酰基-tRNA形成系统中

Distinct genetic code expansion strategies for selenocysteine and pyrrolysine are reflected in different aminoacyl‐tRNA formation systems

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