Amino acid sequence of the oligomycin sensitivity‐conferring protein (OSCP) of beef‐heart mitochondria and its homology with the δ‐subunit of the F1‐ATPase of Escherichia coli

摘要

>The complete amino acid sequence of the oligomycin sensitivity-conferring protein (OSCP) of beef-heart mitochondria is reported. The protein contains 190 amino acids and has a molecular mass of 20 967. Its structure is characterized by a concentration of charged amino acids in the two terminal segments (N 1–77 and C 128–190) of the protein, whereas its central region is more hydrophobic. The earlier reported homology of the protein with the δ-subunit of E. coli F₁, based on the terminal amino acid sequences of OSCP, is further substantiated.