Early diabetes mellitus stimulates proximal tubule renin mRNA expression in the rat

Joseph Zimpelmann; Dinender Kumar; David Z Levine; George Wehbi; John D Imig; Luis G Navar; Kevin D Burns

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Early diabetes mellitus stimulates proximal tubule renin mRNA expression in the rat

机译：早期糖尿病会刺激大鼠近端肾小管肾素mRNA表达

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Early diabetes mellitus stimulates proximal tubule renin mRNA expression in the rat.BackgroundEnhanced intrarenal angiotensin II (Ang II) activity may contribute to diabetic nephropathy. The proximal tubule is a proposed site of significant intrarenal Ang II production. We determined the effect of early diabetes on mRNA expression of components of the proximal tubule renin-angiotensin system.

机译：早期糖尿病会刺激大鼠近端肾小管肾素mRNA表达。背景增强的肾内血管紧张素II（Ang II）活性可能导致糖尿病性肾病。近端肾小管是肾内Ang II产生明显的提议部位。我们确定了早期糖尿病对近端肾小管肾素-血管紧张素系统组分mRNA表达的影响。

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《Kidney international.》 |2000年第6期|共11页
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Joseph Zimpelmann; Dinender Kumar; David Z Levine; George Wehbi; John D Imig; Luis G Navar; Kevin D Burns;
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中图分类泌尿科学（泌尿生殖系疾病）;
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1. Urinary podocyte-associated mRNA levels correlate with proximal tubule dysfunction in early diabetic nephropathy of type 2 diabetes mellitus [J] . Ligia Petrica, Sorin Ursoniu, Florica Gadalean, Diabetology and Metabolic Syndrome . 2017,第1期

机译：尿足细胞相关mRNA水平与2型糖尿病早期糖尿病肾病的近端肾小管功能障碍相关
2. Abnormal regulation of proximal tubule renin mRNA in the Dahl/Rapp salt-sensitive rat [J] . Julia E Tank, Orson W Moe, William L Henrich Kidney international. . 1998,第5期

机译：Dahl / Rapp盐敏感性大鼠近端肾小管肾素mRNA异常调节
3. Potassium depletion stimulates mRNA expression of proximal tubule AT1 angiotensin II receptors. [J] . Burns KD, Smith IB Nephron . 1998,第1期

机译：钾耗竭刺激近端小管AT1血管紧张素II受体的mRNA表达。
4. Current perception threshold through sinusoidal electrical stimulation at different frequencies in a comparative assessment for subjects affected and non-affected by diabetes mellitus [C] . Oliveira Franassis B., Fachin-Martins Emerson, Couto-Paz Clarissa C. S., International IEEE/EMBS Conference on Neural Engineering . 2015

机译：在比较评估中对受糖尿病影响和不受糖尿病影响的受试者进行不同频率的正弦电刺激的当前感知阈值
5. An integrated experimental and computational approach to understanding complex disease: Differential gene expression in type 2 diabetes mellitus [D] . McEachin, Richard C. 2004

机译：理解复杂疾病的综合实验和计算方法：2型糖尿病的差异基因表达
6. Renin and renin mRNA in proximal tubules of the rat kidney. [O] . M Chen, M P Harris, D Rose, 1994

机译：大鼠肾脏近端小管中的肾素和肾素mRNA。
7. Early diabetes mellitus stimulates proximal tubule renin mRNA expression in the rat [O] . Zimpelmann Joseph, Kumar Dinender, Levine David Z., 2000

机译：早期糖尿病会刺激大鼠近端肾小管肾素mRNA表达

Early diabetes mellitus stimulates proximal tubule renin mRNA expression in the rat

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