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Granulicatella adiacens and Early-Onset Sepsis in Neonate

机译:重生的花粉菌和新生儿败血症

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To the Editor: Granulicatella and Abiotrophia, formerly known as nutritionally variant streptococci, are normal . ora of the human upper respiratory, gastrointestinal, and urogenital tracts (1). G. adiacens has been associated with bacteremia and endovascular, central nervous system, ocular, oral, bone and joint, and genitourinary infections (1–4).Although streptococci are a frequent cause of early-onset sepsis in newborns, non–group B or D streptococci comprise only ≈1% of cases of early-onset neonatal sepsis; the condition is primarily associated with viridans streptococci (5). This report describes a male infant with early-onset sepsis caused by G. adiacens. Molecular genetic studies identifi ed the same organism in . ora isolated from the maternal cervix, which suggests vertical transmission.After 36 weeks' gestation, a male infant, weighing 2,850 g, was born by repeat caesarean section to a 37-year-old woman who was negative for group B streptococcus; she began labor without rupture of membranes. Apgar scores were 9 and 9 at 1 and 5 minutes, respectively. Respiratory distress developed in the infant within an hour of birth. Peripheral blood and cerebrospinal . uid (CSF) samples were obtained, and intravenous ampicillin (150 mg/kg every 12 h) and gentamicin (4 mg/kg every 24 h) were administered. Leukocyte count was 27,000/mm3with 79% polymorphonuclear leukocytes and 2% band forms; platelet count was 223,000/mm3. CSF cell counts were 3 leukocytes/mm3and 18 erythrocytes/mm3
机译:致编辑:Granulicatella和Abiotrophia,以前被称为营养变异链球菌,是正常的。人上呼吸道,胃肠道和泌尿生殖道的口(1)。 G. adiacens与菌血症和血管内,中枢神经系统,眼,口腔,骨骼和关节以及泌尿生殖道感染有关(1-4)。尽管链球菌是新生儿早期败血症的常见原因,但非B组或D链球菌仅占早发新生儿败血症病例的约1%;该病主要与绿色链球菌有关(5)。该报告描述了由G. adiacens引起的具有早发败血症的男婴。分子遗传学研究鉴定出同一生物。妊娠36周后,通过剖腹产再次出生一名体重为B组链球菌的37岁女性,体重2,850 g。她开始工作时没有胎膜破裂。 Apgar在1分钟和5分钟时的得分分别为9和9。婴儿在出生后一小时内出现呼吸窘迫。外周血与脑脊液。 uid(CSF)样品,并静脉注射氨苄西林(每12小时150 mg / kg)和庆大霉素(每24 h 4 mg / kg)。白细胞计数为27,000 / mm3,其中多形核白细胞为79%,条带形式为2%;血小板计数为223,000 / mm3。 CSF细胞计数为3白细胞/ mm3和18红细胞/ mm3

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