To the Editor: Granulicatella and Abiotrophia, formerly known as nutritionally variant streptococci, are normal . ora of the human upper respiratory, gastrointestinal, and urogenital tracts (1). G. adiacens has been associated with bacteremia and endovascular, central nervous system, ocular, oral, bone and joint, and genitourinary infections (1–4).Although streptococci are a frequent cause of early-onset sepsis in newborns, non–group B or D streptococci comprise only ≈1% of cases of early-onset neonatal sepsis; the condition is primarily associated with viridans streptococci (5). This report describes a male infant with early-onset sepsis caused by G. adiacens. Molecular genetic studies identifi ed the same organism in . ora isolated from the maternal cervix, which suggests vertical transmission.After 36 weeks' gestation, a male infant, weighing 2,850 g, was born by repeat caesarean section to a 37-year-old woman who was negative for group B streptococcus; she began labor without rupture of membranes. Apgar scores were 9 and 9 at 1 and 5 minutes, respectively. Respiratory distress developed in the infant within an hour of birth. Peripheral blood and cerebrospinal . uid (CSF) samples were obtained, and intravenous ampicillin (150 mg/kg every 12 h) and gentamicin (4 mg/kg every 24 h) were administered. Leukocyte count was 27,000/mm3with 79% polymorphonuclear leukocytes and 2% band forms; platelet count was 223,000/mm3. CSF cell counts were 3 leukocytes/mm3and 18 erythrocytes/mm3
展开▼