203 Modulation of DNA damage induced apoptosis by the proteasome inhibitor bortezomib (PS) in human colorectal and non-small cell lung cancer cells is p53-dependent and NK-kB-independent

N.Takigawa; S.A.J.Vaziri; T.Mekhail; D.R.Grabowski; K.Chikamori; J.E.Hill; A.V.Gudkov; R.M.Bukowski; R.Ganapathi; M.K.Ganapathi

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203 Modulation of DNA damage induced apoptosis by the proteasome inhibitor bortezomib (PS) in human colorectal and non-small cell lung cancer cells is p53-dependent and NK-kB-independent

机译：203蛋白酶体抑制剂硼替佐米（PS）在人结肠直肠癌和非小细胞肺癌细胞中对DNA损伤诱导的凋亡的调控是p53依赖性和NK-kB依赖性的

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《European Journal of Cancer Supplements》 |2004年第8期|共1页
作者
N.Takigawa; S.A.J.Vaziri; T.Mekhail; D.R.Grabowski; K.Chikamori; J.E.Hill; A.V.Gudkov; R.M.Bukowski; R.Ganapathi; M.K.Ganapathi;
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中图分类肿瘤学;
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1. Proteasome inhibitor PS-341 induces growth arrest and apoptosis of non-small cell lung cancer cells via the JNK/c-Jun/AP-1 signaling. [J] . Yang Y, Ikezoe T, Saito T, Cancer science. . 2004,第2期

机译：蛋白酶体抑制剂PS-341通过JNK / c-Jun / AP-1信号传导诱导非小细胞肺癌细胞的生长停滞和凋亡。
2. TRAIL therapy in non-small cell lung cancer cells: sensitization to death receptor-mediated apoptosis by proteasome inhibitor bortezomib. [J] . Voortman J, Resende TP, Abou-El-Hassan MA, Molecular cancer therapeutics . 2007,第7期

机译：非小细胞肺癌细胞的TRAIL治疗：蛋白酶体抑制剂硼替佐米对死亡受体介导的细胞凋亡的敏感性。
3. Phase II study of the proteasome inhibitor bortezomib (PS-341, Velcade) in chemotherapy-naive patients with advanced stage non-small cell lung cancer (NSCLC). [J] . Li T, Ho L, Piperdi B, Lung cancer: Journal of the International Association for the Study of Lung Cancer . 2010,第1期

机译：蛋白酶体抑制剂硼替佐米（PS-341，Velcade）在未经化疗的晚期非小细胞肺癌（NSCLC）患者中进行的II期研究。
4. Nonclinical Discovery and Development of Bortezomib (PS-341, VELCADE~(R)) a Proteasome Inhibitor for the Treatment of Cancer [C] . Bouchard PR, Juedes M, Nix D, Annual Meeting of the American Society for Veterinary Clinical Pathology . 2004

机译：Bortezomib（PS-341，Velcade〜（R）的非临床发现和发展）一种治疗癌症的蛋白酶体抑制剂
5. Mechanism of 3,3'-diindolylmethane-induced cell death in human C33A cervical cancer cells: Induction of endoplasmic reticulum stress, apoptosis and the role of growth-arrest and DNA-damage genes [D] . Han, Jing Y. 2009

机译：3,3'-二吲哚基甲烷诱导的人C33A宫颈癌细胞死亡的机制：内质网应激，细胞凋亡以及生长停滞和DNA损伤基因的作用
6. p300 regulates p53-dependent apoptosis after DNA damage in colorectal cancer cells by modulation of PUMA/p21 levels [O] . N. Gopalakrishna Iyer, Suet-Feung Chin, Hilal Ozdag, 2004

机译：p300通过调节PUMA / p21水平调节大肠癌细胞DNA损伤后p53依赖性凋亡
7. Reactive Oxygen Species Generation and Mitochondrial Dysfunction in the Apoptotic Response to Bortezomib, a Novel Proteasome Inhibitor, in Human H460 Non-small Cell Lung Cancer Cells [O] . Yi-He Ling, Leonard Liebes, Yiyu Zou, 2003

机译：反应性氧物种产生和线粒体功能障碍在凋亡反应对硼替佐米，一种新型蛋白酶体抑制剂，人H460非小细胞肺癌细胞

203 Modulation of DNA damage induced apoptosis by the proteasome inhibitor bortezomib (PS) in human colorectal and non-small cell lung cancer cells is p53-dependent and NK-kB-independent

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