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Mumps Virus–associated Hemophagocytic Syndrome

机译:腮腺炎病毒相关的噬血细胞综合征

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To the Editor: Virus-associatedhemophagocytic syndrome (VAHS) isa fulminant disorder associated withsystemic viral infection and is charac-terized pathologically by the prolifer-ation of hemophagocytic histiocytesin the lymphoreticular tissues. Herewe report a case of mumps VAHS fol-lowing parotitis and pancreatitis.A 39-year-old, previously healthywoman sought treatment for abdomi-nal pain on June 14, 2002. On physicalexamination, her bilateral parotidglands were swollen, and her leftupper quadrant was tender. Laboratorystudies showed a leukocyte count of4,640/mm3, a hemoglobin concentra-tion of 13.9 g/dL, and a platelet countof 19.1 × 104/mm3. The level of amy-lase was elevated in her blood (1,613IU/L; normal 50–160 IU/L) and urine(12,940 IU/L; normal 200–1,100IU/L). Her level of pancreaticenzymes was also elevated: lipaselevel was 194 IU/L (normal 7–60IU/L) and phospholipase A2 level was1,340 ng/dL (normal 130–400 ng/dL).Parotitis and acute pancreatitis due toa mumps virus infection were diag-nosed. After supportive therapy, thelaboratory abnormalities improved
机译:致编辑:病毒相关性血细胞吞噬综合症(VAHS)是与全身性病毒感染相关的暴发性疾病,其病理特征是通过淋巴网状组织中吞噬性吞噬组织细胞的增生。在此,我们报告了一例继发腮腺炎和胰腺炎后出现腮腺炎VAHS的病例。一名39岁,以前健康的女性于2002年6月14日寻求治疗腹部疼痛。经身体检查,她的双侧腮腺肿胀,左上象限为投标。实验室研究显示白细胞计数为4,640 / mm3,血红蛋白浓度为13.9 g / dL,血小板计数为19.1×104 / mm3。她的血液(1613IU / L;正常50-160 IU / L)和尿液(12940 IU / L;正常200-1100IU / L)中的淀粉酶水平升高。她的胰腺酶水平也升高了:脂肪酶水平为194 IU / L(正常7-60IU / L),磷脂酶A2水平为1,340 ng / dL(正常130-400 ng / dL)。腮腺炎病毒引起的胰腺炎和急性胰腺炎诊断感染。支持治疗后,实验室异常改善

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