Fluoroquinolone Use and Clostridium difficile–Associated Diarrhea

摘要

We performed a case-control study to evaluate theassociation between antibiotic use and Clostridiumdifficile–associated diarrhea (CDAD), matching for admis-sion unit and time at risk for CDAD. A multivariable regres-sion model showed that treatment with fluoroquinolones(odds ratio 12.7; 95% confidence interval 2.6 to 61.6) wasthe strongest risk factor for CDAD.