Selection of antibiotics for XDR - A. baumanni and P. aeruginosa bacteremia in a burn ICU

摘要

Background: Acinetobacter Baumannii and Pseudomonas aeruginosa are the nosocomial pathogens in burn patients. Both are instrinsically resistant to a wide range of antibiotics and are able to become resistant to any antimicobial agents. From a clinical perspective, XDR P. aeruginosa and A. baumannii isolates that present resistant to carbapenems represent the most challenging pathogens, since carbapenems are the most potent agents against these organisms. Moreover, a few therapeutic options remain available for the treatment of XDR P.