Clinical study on efficacy and safety of piperamisinin (dihydroartemisinin-piperaquine) in uncomplicated falciparum malaria

摘要

Background: Dihydroartemisinin and piperaquine phosphate co-formulated tablets manufactured from Pharmaceutical Companies of Republic of China namely Artekin and Artepip had been studied in Clinical Research Unit (Malaria) No. (1) DSGH (1000-Beds) Mingalardon in 2006-2008 for the treatment of uncomplicated falciparum malaria and it was found to be safe and effective. Piperamisinin, a combined tablet, containing 50mg dihydroartemisinin and 350 mg piperaquine phosphate, is first produced from Myanmar Pharmaceutical Factory (MPF) of Ministry of Industry in 2009.