EVALUATING EFFICACY OF H-4 COMPOUND AEROSOL NEBULIZATION IN SPUTUM POSITIVE TUBERCULOSIS SUBJECTS (INCLUDING NEWLY DIAGNOSED amp; EXTENSIVE DRUG RESISTANCE TUBERCULOSIS) -A OPEN LEVEL PILOT CLINICAL STUDY

摘要

Aerosol prepared by the hydroalcoholic extract of H-4 compound (having Dalchini, Tejpatra, Lavang and Talishapatra in the ratio of 4:2:1:1) given through nebulization machine twice in a day in the dose of 2.5ml for 10 days completely convert sputum positive tubercular patients into sputum negative for AFB, relive the symptoms of tuberculosis in newly diagnosed cases and its use for 10 days help in regenerating lung parenchyma as evidenced by radiological changes. This drug along with some oral Ayurvedic medicines can be successfully used for the management of newly diagnosed sputum positive tubercular subjects without using any conventional anti-tubercular drug. Aerosol prepared by hydroalcoholic extract of H-4 compound and Shirisha (Albizzia lebback) given through nebulizer machine in the dose of 3ml (1.5ml + 1.5ml) for 10 days converts extensive drug resistance sputum positive tubercular patients to sputum negative for AFB and significantly reduce the presenting symptoms including cough, dyspnea, expectoration and chest pain. The drug is clinically proven to have anti-tubercular property. Inventor: Dr. Divya Kajaria, Department of Kayachikitsa, All India Institute of Ayurveda, New Delhi. Assignee: Dr. Divya Kajaria, Department of Kayachikitsa, All India Institute of Ayurveda, New Delhi.