Predictive factors for sustained virological response in the treatment of patients with chronic hepatitis C

摘要

Background: The goal of antiviral therapy in patients with chronic hepatitis C is to prevent progression of the disease. The most important treatment response is the absence of viral RNA six months after discontinuation the therapy, defined as the sustained virological response (SVR). Successful therapy depends on many factors that are in association with the virus itself and/or infected person. The aim of the investigation was identifying some characteristics of the patients and hepatitis C virus as pre-treatment predictive factors for achieving SVR.