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Application of Measurements of Transepithelial Electrical Resistance of Intestinal Epithelial Cell Monolayers To Evaluate Probiotic Activity

机译:肠上皮细胞单层跨上皮电阻测量在评估益生菌活性中的应用

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Among five potentially probiotic lactobacilli investigated, Lactobacillus plantarum MF1298 and Lactobacillus salivarius DC5 showed the highest increase in the transepithelial electrical resistance (TER) of polarized monolayers of Caco-2 cells, and this increase was shown to be dose dependent. Furthermore, preincubation with MF1298 attenuated a decrease in TER induced by Listeria monocytogenes.
机译:在研究的五种可能的益生菌乳杆菌中,植物乳杆菌MF1298和唾液乳杆菌DC5表现出Caco-2细胞极化单层的跨上皮电阻(TER)升高最高,并且该升高表现为剂量依赖性。此外,与MF1298的预孵育减弱了由单核细胞增生李斯特菌诱导的TER的降低。

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