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首页> 外文期刊>Clinical Chemistry: Journal of the American Association for Clinical Chemists >Postpartum Determination of Umbilical Artery Blood Gases: Effect of Time and Temperature
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Postpartum Determination of Umbilical Artery Blood Gases: Effect of Time and Temperature

机译:产后脐动脉血气的测定:时间和温度的影响

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Determination of cord blood gases and pH is recommended in all neonates with low Apgar scores to distinguish metabolic acidosis from hypoxemia or from other causes that might result in low Apgar scores (1). Although the metabolic acidosis found in cord blood is a poor predictor of long-term neurological injury (2), assessment of umbilical cord blood gas is helpful to exclude intrapartum or birth events that cause acidosis and serves as legal evidence against any alleged association with poor outcome (3).Textbook recommendations for postpartum umbilical cord blood sampling include immediate transport of the blood in a heparin-containing syringe placed in a plastic sack containing crushed ice (4). Several studies have previously questioned the utility of this method (5)(6)(7)(8)(9)(10). Sato and Saling (5) evaluated pH values after only 30 min and at every hour up to 7 h in 30 blood samples stored at room temperature and in 30 different samples stored in a refrigerator. They concluded that if fetal blood has to be stored for 50 min, it must be kept refrigerated to inhibit autoxidation. Hilger et al. (6) evaluated the sequential changes in gases and pH in blood taken from the umbilical vein or from a superficial placental vein at 15-min intervals and at room temperature only. They found that as long as blood was taken from the cord vein, the gases and pH were not affected by as long as 1 h delay in sampling. Pel and …
机译:建议在所有Apgar得分低的新生儿中测定脐带血气体和pH值,以区分代谢性酸中毒与低氧血症或其他可能导致Apgar得分低的原因(1)。尽管脐带血中发现的代谢性酸中毒不能很好地预测长期神经系统损伤(2),但是脐带血气的评估有助于排除会引起酸中毒的产程或出生事件,并可以作为法律依据,以防止任何所谓的与酸中毒的关联结果(3)。教科书中有关产后脐带血采样的建议包括立即在装有碎冰的塑料袋中的含肝素的注射器中运输血液(4)。先前有几项研究质疑此方法的实用性(5)(6)(7)(8)(9)(10)。 Sato和Saling(5)仅在30分钟后和每小时最多7小时后评估了室温下存储的30个血液样本和冰箱中存储的30个不同样本的pH值。他们得出结论,如果胎儿血液必须保存> 50分钟,则必须将其冷藏以抑制自氧化。 Hilger等。 (6)评估了从脐静脉或胎盘浅静脉抽取的血液中气体和pH值的连续变化,间隔为15分钟,且仅在室温下进行。他们发现,只要从脐带静脉采血,采样时间延迟1小时就不会影响气体和pH值。佩尔和…

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