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首页> 外文期刊>British Journal of Cancer >Influence of segmental chromosome abnormalities on survival in children over the age of 12 months with unresectable localised peripheral neuroblastic tumours without MYCN amplification
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Influence of segmental chromosome abnormalities on survival in children over the age of 12 months with unresectable localised peripheral neuroblastic tumours without MYCN amplification

机译:分段染色体异常对未切除MYCN扩增的局限性周围神经母细胞瘤12个月以上儿童存活的影响

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摘要

Background:The prognostic impact of segmental chromosome alterations (SCAs) in children older than 1 year, diagnosed with localised unresectable neuroblastoma (NB) without MYCN amplification enrolled in the European Unresectable Neuroblastoma (EUNB) protocol is still to be clarified, while, for other group of patients, the presence of SCAs is associated with poor prognosis.
机译:背景:在欧洲不可切除神经母细胞瘤(EUNB)方案中,未诊断为MYCN扩增的局限性不可切除神经母细胞瘤(NB)被诊断为1岁以上儿童节段性染色体改变(SCA)对预后的影响尚待阐明,而对于其他SCA患者的存在与预后不良有关。

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