Basal core promoter mutation is associated with progression to cirrhosis rather than hepatocellular carcinoma in chronic hepatitis B virus infection

C-M Chu; C-C Lin; Y-C Chen; W-J Jeng; S-M Lin; Y-F Liaw

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Basal core promoter mutation is associated with progression to cirrhosis rather than hepatocellular carcinoma in chronic hepatitis B virus infection

机译：在慢性乙型肝炎病毒感染中，基础核心启动子突变与肝硬化而不是肝细胞癌的进展有关

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Background:As most cases of hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) have concurrent cirrhosis, viral factors identified to be associated with HCC might be related to cirrhosis rather than HCC.

机译：背景：由于大多数与乙型肝炎病毒（HBV）相关的肝细胞癌（HCC）病例并发肝硬化，因此确定与HCC相关的病毒因素可能与肝硬化有关，而不是HCC。

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《British Journal of Cancer 》 |2012年第12期| 共6页
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C-M Chu; C-C Lin; Y-C Chen; W-J Jeng; S-M Lin; Y-F Liaw;
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1. Basal core promoter mutation is associated with progression to cirrhosis rather than hepatocellular carcinoma in chronic hepatitis B virus infection [J] . C-M Chu, C-C Lin, Y-C Chen, British Journal of Cancer . 2012 ,第12期

机译：在慢性乙型肝炎病毒感染中，基础核心启动子突变与肝硬化而不是肝细胞癌的进展有关
2. The relationship between the hepatitis B virus base core and precore/core promoter mutations and the development of cirrhotic hepatocellular carcinoma and noncirrhotic hepatocellular carcinoma [J] . 徐尧江中国医学文摘：内科学分册（英文版） . 2013 ,第001期

机译：乙型肝炎病毒基础核心和前核心/核心启动子突变与肝硬化肝细胞癌和非肝硬化肝细胞癌发展的关系
3. Hepatitis B virus genotype and basal core promoter/precore mutations are associated with hepatitis B-related acute-on-chronic liver failure without pre-existing liver cirrhosis. [J] . Ren X, Xu Z, Liu Y, Journal of viral hepatitis. . 2010 ,第12期

机译：乙型肝炎病毒基因型和基础核心启动子/前核心突变与乙型肝炎相关的慢性慢性肝功能衰竭相关，而无先前存在的肝硬化。
4. Herbal Medicine Containing Aristolochic Acid and the Risk of Hepatocellular Carcinoma in Patients with Hepatitis C Virus Infection: A Nationwide Population-Based Cohort Study in Taiwan [C] . Wen-Chao Ho, Chi-Jen Chen, Yao-Hsu Yang, Joint annual meeting of the International Society of Exposure Science and the International Society for Environmental Epidemiology . 2018

机译：含有马兜铃酸的草药和丙型肝炎病毒感染患者肝细胞癌的风险：台湾全国性人群研究
5. Viral mutations and natural course of HBeAg negative chronic hepatitis B virus infection. [D] . Chan, Lik Yuen Henry. 2001

机译：HBeAg阴性慢性乙型肝炎病毒感染的病毒突变和自然病程。
6. Basal core promoter mutation is associated with progression to cirrhosis rather than hepatocellular carcinoma in chronic hepatitis B virus infection [O] . C-M Chu, C-C Lin, Y-C Chen, 2012

机译：在慢性乙型肝炎病毒感染中基础核心启动子突变与肝硬化而不是肝癌的进展有关
7. Hepatitis B virus genotype and basal core promoter/precore mutations are associated with hepatitis B-related acute-on-chronic liver failure without pre-existing liver cirrhosis [O] . Ren, X, Xu, Z, Liu, Y, 2010

机译：乙型肝炎病毒基因型和基础核心启动子/前核心突变与乙型肝炎相关的慢性慢性肝功能衰竭相关，而无先前存在的肝硬化
8. Hepatitis B Virus Infection and Hepatocellular Carcinoma: Correlation between IgM Antibody to Hepatitis B Core Antigen, Hepatitis B e Antigen, and Hepatitis B DNA. [R] . Sjogren, M. H., Dusheiko, G. M., Kew, M. C., 1988

机译：乙型肝炎病毒感染和肝细胞癌：乙型肝炎核心抗原，乙型肝炎抗原和乙型肝炎DNa的Igm抗体之间的相关性。

Basal core promoter mutation is associated with progression to cirrhosis rather than hepatocellular carcinoma in chronic hepatitis B virus infection

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