Hypoxia triggers a Nur77|[ndash]||[beta]|-catenin feed-forward loop to promote the invasive growth of colon cancer cells

S K Y To; W-J Zeng; J-Z Zeng; A S T Wong

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Hypoxia triggers a Nur77|[ndash]||[beta]|-catenin feed-forward loop to promote the invasive growth of colon cancer cells

机译：缺氧触发Nur77 | ndash |ββ-catenin前馈环，促进结肠癌细胞的侵袭性生长

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Background:β-Catenin is a potent oncogenic protein in colorectal cancer (CRC), but the targets and regulation of this important signalling molecule are not completely understood. Hypoxia is a prominent feature of solid tumours that contributes to cancer progression.

机译：背景：β-连环蛋白是结直肠癌（CRC）中有效的致癌蛋白，但尚未完全了解这一重要信号分子的靶标和调控。缺氧是实体瘤的显着特征，可导致癌症进展。

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《British Journal of Cancer》 |2014年第4期|共11页
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S K Y To; W-J Zeng; J-Z Zeng; A S T Wong;
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中图分类肿瘤学;
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1. Hypoxia-inducible factor-1 alpha and Wnt/beta-catenin signaling pathways promote the invasion of hypoxic gastric cancer cells [J] . Liu Hong-Lan, Liu Dang, Ding Guang-Rong, Molecular medicine reports . 2015,第3aPta2期

机译：缺氧诱导因子-1α和Wnt /β-catenin信号通路促进缺氧胃癌细胞的侵袭
2. Hypoxia-inducible factor-1 alpha and Wnt/beta-catenin signaling pathways promote the invasion of hypoxic gastric cancer cells [J] . Liu Hong-Lan, Liu Dang, Ding Guang-Rong, Molecular medicine reports . 2015,第3aPta1期

机译：缺氧诱导因子-1α和WNT /β-连环蛋白信号传导途径促进缺氧胃癌细胞的侵袭
3. Upregulation of GNL3 expression promotes colon cancer cell proliferation, migration, invasion and epithelial- mesenchymal transition via the Wnt/beta-catenin signaling pathway [J] . Tang Xi, Zha Lang, Li Hui, Oncology reports . 2017,第4期

机译：GNL3表达的上调促进结肠癌细胞增殖，迁移，侵袭和上皮间充质转换通过WNT /β-连环蛋白信号通路
4. Beta-catenin in Evaluation of Dynamics of Laryngeal Cancer Growth [C] . W. Pietruszewska, J. Hobos, A. Murlewska, European Congress of Oto-Rhino-Laryngology, Head and Neck Surgery . 2004

机译：β-catenin评估喉癌生长的动态
5. PAI-1 secreted from metastatic ovarian cancer cells triggers the tumor-promoting role of the mesothelium in a feedback loop to accelerate peritoneal dissemination [D] . Peng Yang, 彭杨 2019

机译：转移性卵巢癌细胞分泌的PAI-1在反馈回路中触发上皮的肿瘤促进作用，从而加速腹膜的扩散
6. Hypoxia triggers a Nur77–β-catenin feed-forward loop to promote the invasive growth of colon cancer cells [O] . S K Y To, W-J Zeng, J-Z Zeng, 2014

机译：缺氧触发Nur77-β-catenin前馈环促进结肠癌细胞的侵袭性生长
7. Hypoxia triggers a Nur77-beta-catenin feed-forward loop to promote the invasive growth of colon cancer cells [O] . To S. K. Y., Zeng W-J, Zeng J-Z, 2014

机译：缺氧触发Nur77-β-catenin前馈环，促进结肠癌细胞的侵袭性生长

Hypoxia triggers a Nur77|[ndash]||[beta]|-catenin feed-forward loop to promote the invasive growth of colon cancer cells

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