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Clinical significance of p95HER2 overexpression, PTEN loss and PI3K expression in p185HER2-positive metastatic breast cancer patients treated with trastuzumab-based therapies

机译:曲妥珠单抗治疗的p185HER2阳性转移性乳腺癌患者中p95HER2过表达,PTEN缺失和PI3K表达的临床意义

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Retraction to: British Journal of Cancer (2014) 110, 19681976; 10.1038/bjc.2014.72It has been brought to our attention that, as a result of a miscommunication, the antibody used in this study in order to determine the expression of p95 HER2 in metastatic breast cancer patients is in fact directed against p95 NBS1, a component of the MRN complex, and is completely unrelated to p95 HER2. Therefore, a relationship between p95 HER2 overexpression and outcome cannot be established based on the results described and we wish to retract our paper.
机译:收录至:《英国癌症杂志》(2014)110,19681976; 10.1038 / bjc.2014.72引起我们注意的是,由于沟通不畅,本研究中用于确定转移性乳腺癌患者中p95 HER2表达的抗体实际上针对的是p95 NBS1, MRN复合体的组成部分,与p95 HER2完全无关。因此,基于所描述的结果无法建立p95 HER2过表达与结果之间的关系,我们希望撤回本文。

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