Dual Neurotoxicity (Acute Encephalopathy followed by Delayed Myeloneuropathy) following Dichlorovos Poisoning

摘要

Organophosphate compounds (OPCs) are used as pesticides, and suicidal ingestion is the most common mode of OPC poisoning inIndia. Several clinical syndromes, including acute muscarinic syndrome, acute encephalopathy, intermediate nicotinic syndrome,delayed neuropathy, and rarely Guillain Barre-like syndrome, extrapyramidal syndrome, dual neurotoxicity, chronicneuropsychiatric disorder, and war gas poisoning can be encountered, depending on the dose and the type of organophosphateexposure. Dual neurotoxicity is extremely rare and the clinical profile and electrophysiological features of one such case followingsuicidal ingestion of the organophosphate dichlorovos are described along with a brief review of the literature.