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Asthma at the 2016 American Thoracic Society International Conference

机译:哮喘在2016年美国胸科学会国际会议上

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The Year in Review in asthma was presented by Dr. Akshay Sood from the University of New Mexico, featuring several high profile articles published over the last year. Of particular interest, favorable phase 3 data were presented supporting the use of reslizumab, a humanized monoclonal antibody against IL5, in the treatment of moderate-to-severe asthma in patients with blood eosinophil counts greater than 400 cells per microliter (1). Patients receiving reslizumab had fewer asthma exacerbations over 1 year than patients receiving placebo in two duplicate studies published as a single manuscript. Reslizumab was approved earlier this year in the United States for the treatment of severe asthma.
机译:新墨西哥大学的Akshay Sood博士介绍了“哮喘年度回顾”,其中包括去年发表的几篇引人注目的文章。特别令人感兴趣的是,提供了有利的第3期数据,支持使用瑞利珠单抗(一种抗IL5的人源化单克隆抗体)治疗嗜酸粒细胞计数大于400细胞/微升的患者中重度哮喘(1)。在发表为单篇手稿的两项重复研究中,接受瑞舒单抗治疗的患者在1年内的哮喘急性发作率低于接受安慰剂的患者。 Reslizumab于今年早些时候在美国获批用于治疗严重哮喘。

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