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Tea decoctions prevent body weight gain in rats fed high-fat diet; black tea being more efficient than green tea

机译:茶汤可防止高脂饮食大鼠体重增加。红茶比绿茶更有效

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Abstract Background/Aims In contrast to the usual tea infusion, the anti-obesity effect of tea decoction (TD) is poorly documented. Here, we compared and contrasted the chronic effect of short-time decoction (15-min) of green versus black tea (GTD, BTD) prepared at a dose of 5% on lipid digestion and weight gain in rats fed high-fat diet (HFD) for 10 weeks. Methods The rats were assigned into three groups (n?=?10–12 each) and given ad libitum the HFD?+?water (CTRL) or {GTD} (GTGr) or {BTD} (BTGr). The food and fluid intake were measured daily and weight gains once/week. The fecal matters were collected twice/week for TPC, caffeine, total lipids and triglycerides (TG) analysis. In addition, the liver, perirenal and epididymal adipose tissues (AT) were removed and blood was collected for the same analysis and leptine level. Results 10-weeks {TD} consumption increased fecal {TG} excretion (+170 in {GTGr} and?+230% in BTGr; P?
机译:摘要背景/目的与常规茶饮相反,茶汤(TD)的抗肥胖作用文献很少。在这里,我们比较并对比了以5%剂量制备的绿茶与红茶(GTD,BTD)的短时煎煮(15分钟)对高脂饮食大鼠脂质消化和体重增加的慢性影响( HFD)持续10周。方法将大鼠分为三组(每组n = 10-12),并随意给予HFD +水(CTRL)或{GTD}(GTGr)或{BTD}(BTGr)。每天测量食物和液体摄入量,每周增加体重一次。每周两次收集粪便,以进行TPC,咖啡因,总脂质和甘油三酸酯(TG)分析。另外,去除肝脏,肾周和附睾脂肪组织(AT),并收集血液用于相同的分析和瘦素水平。结果10周{TD}摄入量增加了粪便{TG}排泄({GTGr}中的+170和BTGr中的+ 230%; P <0.001,而CTRL)。在{GTGr}和BTGr中,肝脏{TG}分别降低了25%和35%(P <0.001,与CTRL相比),血浆{TG}降低了36.6和48%(P 0.01,与CTRL比)。 {GTGr}的{AT}增益降低了26.5和56.4%,而{BTGr}的{AT}增益降低了60%(P <0.001,而CTRL)。 {AT}的降低与瘦素水平的降低27%和59%相一致(与CTRL相比P 0.001)和{GTGr}和{BTGr}的体重增加分别降低21%和55%(P <0.01对vs CTRL)。结论慢性{GTD}和{BTD}可以预防高脂饮食大鼠肝脏中的脂肪储存,降低血脂和葡萄糖,增加TG的粪便排泄,降低{AT}和体重增加,与{BTD}相比,其作用强GTD。因此,这些含有大量{TPC}和咖啡因的饮料可以构成预防肥胖的天然替代品。

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