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Radiotherapy response and related clinicopathological factors of patients with cervical cancer

机译:宫颈癌患者的放射治疗反应及相关的临床病理因素

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The incidence of cervical cancer was still high in RSCM, and most patients exhibited advanced stage disease. For approximately 20–50% of these patients, radiotherapy did not achieve local tumor control. Achieving complete response and eradication of locoregional tumors in patients with cervical cancer should improve survival rates. Therefore, the purpose of this study was to determine the radiotherapy response, and related clinic-pathologic characteristics of patients with cervical cancer at our hospital. We used secondary data from 123 patients with stage IIA-IIIB cervical cancer who underwent radiation therapy at our hospital from January, 2014 to December, 2015. We recorded age, body mass index, blood pressure, hemoglobin, blood leucocyte count, serum albumin, largest tumor diameter FIGO staging, and pathologic characteristics for each patient. During radiation until 3 months post radiation, we also noted any gastrointestinal, genitourinary, and hematologic side effects. Our results indicate that acute side effects were generally tolerable during and three months post radiation therapy. The clinicopathologic characteristic that significantly related to complete response was largest tumor diameter.
机译:RSCM中子宫颈癌的发生率仍然很高,大多数患者表现出晚期疾病。在这些患者中,约20–50%的放疗未能实现局部肿瘤控制。在宫颈癌患者中实现局部肿瘤的完全缓解和根除应提高生存率。因此,本研究的目的是确定我院宫颈癌患者的放射治疗反应及相关的临床病理特征。我们使用了2014年1月至2015年12月在我院接受放射治疗的123例IIA-IIIB期宫颈癌患者的二级数据。我们记录了年龄,体重指数,血压,血红蛋白,血白细胞计数,血清白蛋白,每个患者的最大肿瘤直径FIGO分期和病理特征。在放疗期间直至放疗后3个月,我们还注意到了任何胃肠道,泌尿生殖道和血液学方面的副作用。我们的结果表明,在放射治疗期间和之后三个月,急性副作用通常是可以忍受的。与完全缓解密切相关的临床病理特征是最大的肿瘤直径。

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