Multi-modal realignment treatment decreases pain in people with medial tibiofemoral osteoarthritis

摘要

Summary of: Hunter D et al (2012) Realignment treatment for participation), use of ambulation aids and known causes for medial tibiofemoral osteoarthritis: randomised trial. of inflammatory arthritis. Interventions: Active treatment Ann Rheum Dis 71: 1658C1665. [Prepared by K?re B Hagen included a valgus knee brace and customised neutral foot and Margreth Grotle, CAP Editors.] orthoses and motion control shoes, while control treatment was a neutral knee brace that does not have any varus/ Question: Does a multi-modal realignment treatment valgus angulation and a flat unsupportive foot orthosis and relieve pain and improve function among persons with shoes with a flexible mid-sole. A run-in design was used in medial tibiofemoral osteoarthritis (OA)? Design: A double- order to maximise the likelihood of recruiting subjects who blind (participant and assessor) 30 week randomised would remain in the trial. Participants were randomised to crossover trial. Setting: Participants were recruited from receive either active treatment or control treatment for 12 rheumatology and orthopaedic hospital departments and weeks. Following a 6-week washout period, the alternative from persons already recruited for other clinical trials, treatment was assigned for the final 12 weeks. Outcome using various forms of advertising in local public media measures: Primary outcomes were the WOMAC Pain (0C in New England, USA. Participants: Ambulatory persons 20) and Function (0C68) subscales. Results: 80 participants fulfilling American College of Rheumatology criteria for were randomised and 56 completed the study. The active knee OA, with radiographically confirmed osteophytes and realignment intervention had effect on pain with a ?1.82 pain, aching or stiffness on most of the past 30 days, and unit decrease (95% CI ?3.05 to ?0.60), and a non-significant radiographic evidence of disease in the medial tibiofemoral effect on function [2.90 unit decrease (95% CI ?6.60 to compartment were included. Key exclusion criteria 0.79)] compared with the control condition. Conclusion: included predominant lateral tibiofemoral or patellofemoral Multi-modal realignment treatment can decrease pain in involvement, low WOMAC Pain scores (a minimal score of persons with medial tibiofemoral OA. at least 2 out of 5 on at least 2 of the 5 questions was required.