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The effect of different suctioning modalities on physiologic measures and the incidence of ventilator associated pneumonia

机译:不同抽吸方式对生理指标和呼吸机相关性肺炎发生率的影响

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Objective: To compare physiologic measures and the incidence of ventilator associated pneumonia (VAP) using different modalities of endotrachael tube (ETT) suctioning. Methods: A Quasi-experimental design was used with 80 adults in an intensive care unit. Two modalities of suctioning were compared: 1) not instilling normal saline (NS) into the ETT before suctioning, and 2) instilling NS into the ETT tube before suctioning. The outcome variables were: physiologic measures (heart rate, respiratory rate and blood pressure and oxygen saturation), the incidence of Ventilator Associated Condition (VAC) and Possible Ventilator Associated Pneumonia (PVAP) at day 5 after mechanical ventilation. Results: There were no differences in the physiologic measures assessed at day 5 and a significantly higher rate of VAC in patients who had NS installed (p = .009). Four patients developed PVAP compared to 10 patients in group 2 where NS was installed but that did to reach significance (p = .077). Factors associated with VAC were age, WBC > 12,000, antibiotic use, amount of secretions, and NS installation. The same factors were associated with the development of PVAP with the exception of NS installation which did not reach significance. Conclusions: Installing NS in the ETT tube did not result in significant physiologic changes at day 5, and more rates of VAC and PVAP were noted. Therefore, the use of this procedure is questionable and further studies are needed to provide conclusive evidence.
机译:目的:比较采用不同形式的腔内插管(ETT)抽吸的生理指标和呼吸机相关性肺炎(VAP)的发生率。方法:在重症监护病房中对80名成人进行了准实验设计。比较了两种抽吸方式:1)在抽吸之前不向ETT中滴注生理盐水(NS),以及2)在抽吸之前向ETT管中滴注NS。结果变量为:机械通气后第5天的生理指标(心率,呼吸频率以及血压和氧饱和度),呼吸机相关状况(VAC)和可能的呼吸机相关性肺炎(PVAP)发生率。结果:在第5天评估的生理指标没有差异,并且安装NS的患者的VAC比率显着更高(p = .009)。与安装了NS的第2组的10例相比,有4例发生了PVAP,但确实达到了显着水平(p = .077)。与VAC相关的因素包括年龄,WBC> 12,000,抗生素的使用,分泌物的量和NS的安装。除NS安装不重要外,与PVAP的开发相关的因素相同。结论:在第5天,在ETT管中安装NS不会导致明显的生理变化,并且注意到VAC和PVAP的发生率更高。因此,该程序的使用值得怀疑,需要进一步研究以提供确凿的证据。

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