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Ocular sarcoidosis and tuberculous lymphadenopathy: coincidence or real association

机译:眼结节病和结核性淋巴结肿大:巧合或真实关联

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Tuberculosis and sarcoidosis share similarity in histopathologic findings and clinically occur in association with each other occasionally. Tuberculosis should always be ruled out before the diagnosis of sarcoidosis. But, the diagnosis is often complicated, especially in extrapulmonary cases. Here we present a case of bilateral vitreous hemorrhage with uveitis. Ocular sarcoidosis was initially diagnosed based on the characteristic ocular findings, negative results on chest radiography, tuberculosis culture, and polymerase chain reaction of aqueous, as well as simultaneous presence of panda and lambda sign on gallium-67 scans. The ocular condition improved after pars plana vitrectomy and systemic steroid therapy. However, TB lymphadenopathy but no recurrent ocular inflammation was found 6?years later. The patient received anti-TB treatment for 6?months thereafter. The eyes remained silent except cataract progression and glaucoma under two medications during this period. In conclusion, TB could occur coincidently or in association with sarcoidosis, continued follow-up is important for patients with ocular sarcoidosis.
机译:结核和结节病在组织病理学发现中具有相似性,临床上偶尔会相互关联。诊断结节病之前,应始终排除结核病。但是,诊断通常很复杂,尤其是在肺外病例中。在这里,我们介绍一例伴葡萄膜炎的双侧玻璃体出血。眼结节病最初是根据眼部特征性发现,胸部X光片检查,结核病培养和水的聚合酶链反应以及在67镓扫描中同时存在熊猫和λ征而诊断出来的。平板玻璃体切除术和全身类固醇治疗后,眼部状况得到改善。但是6年后未发现结核性淋巴结病,但未见复发性眼部炎症。此后此患者接受了6个月的抗结核治疗。在此期间,除了白内障进展和青光眼,在两种药物治疗期间,眼睛保持沉默。总之,结核病可能同时发生或与结节病有关,对于眼结节病患者,继续随访很重要。

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