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Association between standardized uptake value and survival in patients with locally advanced or metastatic squamous cell head and neck cancer

机译:局部晚期或转移性鳞状细胞癌和头颈癌患者的标准摄取值与生存之间的关系

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Introduction and objective The present study aimed to evaluate the association between tumor Standard Uptake Value (SUVmax) values obtained by PET/CT, and survival in patients with locally advanced or metastatic squamous cell head and neck cancer. Method The present study included 38 patients with locally advanced or metastatic squamous cell head and neck cancer, who were staged using PET/CT at diagnosis. PET/CT imaging findings were evaluated retrospectively. The effect of SUVmax value by PET/CT on overall survival was analyzed. Results The most common tumor localization was laryngeal cancer among 38 patients included in the study (n?=?25, 65.8%). The study group consisted of mostly male patients (n?=?33, 86.8%), and the median age was 58 (range: 24–77). The median SUVmax value was 11 (range: 3–58). Median survival was 32.7 months in patients with SUVmax ≤11 compared to 16.5 months in patients with SUVmax >11 (p?=?0.019).
机译:引言和目的本研究旨在评估PET / CT获得的肿瘤标准摄取值(SUVmax)值与局部晚期或转移性鳞状细胞癌和头颈癌患者的生存率之间的关系。方法本研究纳入了38例局部晚期或转移性鳞状细胞癌,均在诊断时采用PET / CT分期。回顾性评估PET / CT影像学发现。分析了PET / CT得出的SUVmax值对总体生存率的影响。结果在研究中38例患者中,最常见的肿瘤部位是喉癌(n = 25,65.8%)。该研究组主要由男性患者组成(n = 33,占86.8%),中位年龄为58岁(范围:24-77)。 SUVmax中位数为11(范围:3–58)。 SUVmax≤11的患者中位生存期为32.7个月,而SUVmax> 11的患者中位生存期为16.5个月(p?=?0.019)。

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