Supratentorial Mass Lesion Biopsy Using Frameless Stereotactic System; Diagnostic Yield, Surgical Morbidity, and Comparison With Freehand Biopsy

摘要

Objective :The objective of this study is based on a comparison of freehand and stereotactic biopsy regarding diagnostic yield in terms of adequate tissue sample, morbidity in terms of postoperative complications like neurological deficit, bleeding, infection etc. and mortality. Material and Methods :A randomized clinical study was carried out and included 70 patients (35 patients underwent freehand biopsy and 35 patients underwent stereotactic biopsy). The data was collected for variables including age, sex, location and size of tumor. The outcome was assessed by diagnostic yield in terms of adequate tissue sample, morbidity in terms of postoperative complications like neurological deficit, bleeding, infection etc. and mortality between the two groups was compared. Results :Total 70 biopsies were excised and 35 (50%) of them underwent freehand biopsy while the rest of 35 (50%) underwent stereotactic biopsy. Freehand biopsy was associated with 5.71% morbidity, compared to 2.85% morbidity for stereotactic biopsy. Four freehand biopsies (11.42%) and two stereotactic biopsies (5.71%) were non-diagnostic. Statistical analysis showed no significant difference between morbidity in the two groups. The rate of diagnostic failure between two groups was not significantly different with a p-value of 0.673, but it was found significant clinically. Conclusion :Stereotactic biopsy has provided us with a powerful and a safer tool to provide tissue diagnosis with minimal disruption of the normal-functioning studies, though with minimal morbidity. Our study is comparable to other international studies there is very little difference in the morbidity but significant difference in diagnostic yield.