Catastrophic antiphospholipid syndrome presented with sudden renal failure and history of long-lasting psychosis and hypertension in a 42 years old women

摘要

The catastrophic variant of the antiphospholipid syndrome (CASP) is defined as a potential life-threatening variant of antiphospholipid syndrome (APS), which is characterized by multiple small-vessel thrombosis that can lead to organ failure especially renal deterioration. This vaso-occlusive nephropathy mainly affects arterioles, interlobular arteries and glomerular tufts. However, interstitial area and tubules maybe subsequently involved