A previously healthy 16-month-old Korean girl with symptoms of fever, vomiting, and generalized tonic seizure was diagnosed to have Group D non-typhoid Salmonella meningitis. The patient was treated with ceftriaxone (100 mg/kg/day) and amikin (22.5 mg/kg/day) initially and ciprofloxacin (30 mg/kg/day) was added later because of clinical deterioration and disseminated intravascular coagulation. Brain CT performed on the second day showed a well-demarcated low density lesion in the right lentiform nucleus and both caudate nuclei, without evidence of increased intracranial pressure. MRI performed on the 11th day confirmed CT scan findings as well as right subdural fluid collection, brain atrophy, and ventriculomegaly. She underwent subdural drainage and later ventriculo-peritoneal shunt operation. Despite receiving intensive treatment, she still has severe neurologic sequelae. Our case shows that infarctions of basal ganglia and thalami are not specific for tuberculous meningitis and that meningitis complicated by infarction is indicative of grave prognosis.
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机译：先前健康，有发烧，呕吐和全身性强直性抽搐症状的16个月大的韩国女孩被诊断患有D组非伤寒沙门氏菌性脑膜炎。患者最初接受头孢曲松钠（100 mg / kg /天）和阿米金（22.5 mg / kg /天）的治疗，后来由于临床恶化和弥散性血管内凝血而加入环丙沙星（30 mg / kg /天）。第二天进行的脑部CT检查显示右半形核和两个尾状核均划定了低密度病变，而没有颅内压升高的证据。在第11天进行的MRI证实了CT扫描发现以及右硬膜下积液，脑萎缩和脑室肥大。她接受了硬膜下引流，后来进行了心室-腹膜分流手术。尽管接受了强化治疗，她仍然有严重的神经系统后遗症。我们的病例表明，基底节和丘脑梗塞不是结核性脑膜炎的特有症状，脑膜炎并发梗塞可预示严重预后。
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